Evaluation of Antipsychotic Drugs
Psychiatric disorders have become one of the most common diseases worldwide and is growing at a rapid rate, posing a serious threat to human health and social stability.
Our company offers the most comprehensive services for screening and evaluation of antipsychotic drugs based on behavioral testing in rodents. Our experienced experts work with you to select and develop the most appropriate tests to accelerate your drug development program.
Current Status of Development of Drugs for Psychiatric Disorders
- Huge market demand
With the increase of people's social pressure, the number of patients is increasing year by year, and the search for efficient and safe antipsychotic drugs has become more than a dozen urgent.
- Strong dependence of patients on drugs
Psychiatric disorders are often difficult to cure, and patients are highly dependent on medications, often requiring long-term or even lifelong medication to relieve symptoms.
- Large space for drug development
Few drugs with significant breakthrough therapeutic effects have been reported, and existing therapeutic drugs have limited their use and efficacy due to safety and drug resistance issues. Therefore, there is great space for the development of drugs for psychiatric disorders.
Approaches to The Evaluation of Antipsychotic Drugs
Anxiety and depression are the most common and prevalent psychiatric disorders. The anxiety model is mainly divided into conditioned and unconditioned models. The classical test methods for these models are based on the animal's nature of fearing open spaces and the tendency to avoid activities.
We have also developed and offered a variety of behavioral tests with rapid, sensitive responses to antidepressants. In addition, since stress is one of the most important causes of the occurrence of anxiety and depression, it affects behavioral activities such as mental mood, cognitive function, and responsiveness and judgment. Therefore, we offer a variety of methods to assess different aspects of stress behavior.
Our company offers screening and evaluation methods for antipsychotics including but not limited to the following.
| Anxious Behavior | ||
|---|---|---|
| Open filed test | Darkness avoidance test | Elevated plus maze test |
| Vogel conflict test | ||
| Depressive Behavior | ||
| Forced swimming test | Tail suspension test | Open filed test |
| Learned helplessness test | Novelty-suppressed feeding test | Sucrose preference test |
| Stress Behavior | ||
| Restraint test | Conditional defense burial test | Auditory startle test |
Drug Screening and Evaluation Process of Our company
Our company offers a customized testing process based on your specific research needs, including the selection of test subjects, the selection of test methods, the execution of experimental protocols, and data analysis.
Our company applies our specialized behavioral tests to the screening and safety assessment of antipsychotic drugs. We are committed to providing valuable reference results for our clients' drug development projects. If you are interested, please contact us and describe your specific research, and we will be happy to assist you.