Rat Models
Why Are Rat Models Important for Drug Development?
- Similarity of physiological functions. The physiological and biochemical processes of rats are very close to those of humans, which allows the results of drug tests performed on rats to speculate to some extent on their effects in humans.
- Ease of manipulation. Compared to larger animal models, rats are easy and less expensive to raise and handle, facilitating extensive efficacy testing in the early stages of drug discovery.
- Genetic Stability. The relatively stable genome of the rat makes it suitable for genetically related studies, which will provide opportunities to discover new drug targets in drug discovery.
- Abundant models. Disease models based on rats are abundant and diverse, including but not limited to heart disease, diabetes, cancer, neurodegenerative diseases, etc., which is conducive to the screening and optimization of drugs in simulated disease environments.
Abundant Rat Models
We have over 30,000 rat models in a wide variety of species, including rats, blind mole rats, sand rat, cotton rats, Nile grass rats, spiny rats, rice rat, diurnal Sudanese grass rat, South American water rat, long-tailed pygmy rice rat, and diurnal grass rat. They can be used to study a variety of diseases such as cancer, diabetes, Parkinson's disease, Alzheimer's disease, cardiovascular disease, depression, schizophrenia, autism, and more. By observing the lab rats, you can conduct more in-depth research on the pathogenesis of various diseases, pathological changes, drug efficacy and other studies.
Related Services
- Customized disease model service. According to your research needs, we can provide genetic engineering model creation, disease animal model, xenograft model creation and genotyping services.
- Disease model testing services. We can test the effects of specific drugs or treatments in disease models for you.
- Rat model care and management services. Ensure that experimental animals grow in a favorable environment to ensure the accuracy of research results.
- Professional consulting services. We provide free technical consultation and solutions to researchers conducting preclinical studies using animal models.
Related Models
Browse our list of rat models
| Models Name | Cat.No. | Animal Type | Disease Area |
|---|---|---|---|
| Hepatic fibrosis, carbon tetrachloride/dimethylnitrosamine-induced, in rat (Fischer 344) | AB3378 | rat | Fibrosis,hepatic |
| Hepatic fibrosis, choline-deficient/L-amino acid-defined diet-induced, in rat (Fischer 344) | AB3379 | rat | Fibrosis,hepatic |
| Hepatic fibrosis, high-fat diet-induced, in rat (SHR) | AB3380 | rat | Fibrosis,hepatic |
| Hepatic fibrosis, high-salt diet-induced, in rat (SHR) | AB3381 | rat | Fibrosis,hepatic |
| Hepatic fibrosis, Porcine serum-induced, in rat (Fischer 344) | AB3382 | rat | Fibrosis,hepatic |
| Hepatic inflammation, bile duct ligation-induced, in rat (Wistar Kyoto) | AB3383 | rat | Inflammation,hepatic |
| Hepatitis C (HCV) infection, rat Hepacivirus-induced, in rat (Long Evans) | AB3384 | rat | Hepatitis C (HCV) |
| Hepatotoxicity (adverse event), in fasted rat (Fischer 344) | AB3385 | rat | |
| Hepatotoxicity (adverse event), in rat (Fischer 344) | AB3386 | rat | |
| Hepatotoxicity, 2,4-thiazolidinedione-induced, in rat (Fischer 344) | AB3387 | rat | Hepatotoxicity |