The basis of prevention and therapeutics of any infectious disease is the development of precise and dependable diagnostic tests. As such, our company seeks to meet the challenges posed by infectious diseases through the provision of cutting edge diagnostics development services.
Diagnostics Development for Infectious Diseases
- The Need for Effective Diagnostics
Infectious disease diagnosis is important because, to some extent, it can help control infection diseases which pose a huge concern to global health. As for traditional micrsocopy and cultures diagnostics, they are not very specific and sensitive which makes them very slow. There is a greater need to develop advanced diagnostics to address these challenges.
- Companion and Complementary Diagnostics
Both diagnostic methods (companion diagnostics and complementary diagnostics) aid in therapeutics selection for infectious diseases. Companion diagnostics are targeted tests which seek out certain biomarkers or polymorphisms that determine whether a therapeutic response will occur. Conversely, complementary diagnostics are supplemented with certain antimicrobial drugs to establish the existence of resistance or to assess the effectiveness of the therapeutics.
Fig.1 Stochastic DNA dual-walkers for colorimetric detection of bacteria. (Wang C., et al., 2021)
Point-of-Care (POC) Diagnostics of Infectious Diseases
| Methods |
Pros |
Cons |
| Electrochemical biosensors |
High sensitivity, fast response, and low cost |
Weak stability and susceptibility to interference |
| Fluorescence biosensors |
Rapid response, flexibility, and experimental simplicity |
High fluorescence background |
| SERS-based biosensors |
High sensitivity, well multiplexing capabilities, no photobleaching, and low background |
Limited field of view |
| Colorimetric biosensors |
Simplicity and visualized detection |
Inability to achieve quantitative detection and limited sensitivity |
| Chemiluminiscence biosensors |
High sensitivity, wide linear dynamic ranges, simple instrument |
Time-consuming, and enzyme-dependent |
| SPR-based biosensors |
Label-free and real-time detection |
Bulky equipment and expensive |
| Magnetic biosensors |
Low cost, and high signal-to-noise ratio detection |
Shortage of miniaturized magnetic readout systems |
Our Services
We work relentlessly to discover innovative biomarkers, genotypic variability, and molecular targets of infectious diseases. As an established firm specializing in the development of diagnostics, we support the progress of diagnostics for infectious disorders with an array of services.
Biomarker Development
- MicroRNAs (miRNAs) biomarkers
- Protein biomarkers
- Nucleic acid biomarkers
- Metabolite biomarkers
- Host immune response biomarkers
Why Choose Us?
We understand that each infectious disease presents unique challenges, and a one-size-fits-all approach may not be optimal. Therefore, our diagnostics development services offer customized solutions tailored to specific infectious diseases or client requirements. This flexibility allows us to address the diverse diagnostic needs in the field of infectious diseases effectively. If our comprehensive range of services has captured your interest, we wholeheartedly urge you to reach out to us without any hesitation.
References
- Wang Chao, et al. "Point-of-care diagnostics for infectious diseases: From methods to devices." Nano Today 37 (2021): 101092.
- Dailey Peter J., Tarek Elbeik, and Mark Holodniy. "Companion and complementary diagnostics for infectious diseases." Expert Review of Molecular Diagnostics 20.6 (2020): 619-636.
All of our services and products are intended for preclinical research use
only and cannot be used to diagnose, treat or manage patients.
