Banner

Muscle Biopsy Service

Muscle Biopsy Service

The presence of severely injured or dysfunctional mitochondria has become highly contributory toward the pathogenesis of several common human ailments. Mitochondrial function evaluation is currently contingent on invasive tissue biopsies such as muscle biopsy. Protheragen accelerates research and provides crucial platforms that aid in pioneering the research on the mechanisms of mitochondrial diseases and drug development processes for further advanced diagnosis of mitochondrial diseases.

Applications of Muscle Biopsy

Muscle biopsy serves an integral role in preclinical studies of mitochondrial diseases by providing invaluable information regarding the disease process, aiding in the formulation of therapeutic methods, and enhancing new therapeutic development.

  • Providing Histological Analysis
    The muscle biopsy provides a thorough analysis of the pathology of the disease by studying muscle tissue encompassing the shape, structure, and size of muscle fibers. This is highly important for the proper identification of mitochondrial disorders and their pathology.
  • Mitochondrial Quantity and Morphology
    Muscle biopsies also assess the quantity, morphology, structural integrity, and functional activity of mitochondria. This is of utmost importance with respect to the diagnosis of any form of mitochondrial injury or aberration.
  • Detection of Mitochondrial DNA Defects
    Muscle biopsies provide effective approaches to aid and diagnose hereditary disorders of mitochondria by identifying variations and defects found in mitochondrial DNA.
  • Study Energy Metabolism
    With an analysis of muscle biopsy, there is an enhanced understanding of the energy metabolism of mitochondria, such as ATP production and oxidative phosphorylation, which helps identify probable defects in energy metabolism caused by mitochondrial diseases.

Our Services

Protheragen is at the forefront of preclinical research, dedicated to advancing the understanding and treatment of mitochondrial diseases. Our Muscle Biopsy Services serve as a pivotal component in our commitment to providing comprehensive diagnostic solutions.

Precision Sample Collection and Handling

Sample Collection and Handling

With an exceptional degree of expertise, our team excels in carrying out muscle tissue sampling while ensuring its minimal invasiveness and the best sample integrity. The handling and processing of the samples guarantees successful outcomes for all subsequent analytical tests.

Histological Analysis

Histological Analysis

Going further into the microscopic realm, our muscle biopsy services provide comprehensive, detailed histological services. We study the muscle cells at the tissue level and analyze their structure and functions for an accurate diagnosis of mitochondrial diseases.

Immunohistochemistry (IHC)

Immunohistochemistry (IHC)

With advanced immunohistochemistry, we will enhance the detection of specific mitochondrial proteins and other pertinent biomarkers for our diagnostics. This allows us to effectively identify underlying mitochondrial dysfunction within our diagnostics.


Our Advantages

Professional Team

Professional Team

Advanced Technologies

Advanced Technologies

Customized Solutions

Customized Solutions

Competitive Pricing

Competitive Pricing

Employees of the firm Protheragen with proficiency in mitochondria disorders offer muscle biopsy services because, as specialized researchers with years of experience in the field, they are specialists in the area. If you are interested in our services, please feel free to contact us for more detailed information.

For research use only, not for clinical use.