The analysis of mitochondrial function plays a crucial role in investigating intracellular energy metabolism, mechanisms of cell death, and mitochondrial diseases. As a leading provider of services for analyzing mitochondrial function, Protheragen is dedicated to delivering efficient and cost-effective solutions tailored to the specific requirements and circumstances of our clients' projects.
Our Services
Protheragen focuses not only on mitochondrial structure analysis service but also on providing a comprehensive analysis of various mitochondrial functions service. These include mitochondrial membrane potential, mitochondrial calcium leakage, mitochondrial ROS production, mitochondrial antioxidant capacity, mitochondrial aerobic respiration, mitochondrial transport, and mitochondrial apoptosis signal.
Mitochondrial Oxidative Phosphorylation Analysis
Analysis of oxidative phosphorylation and the function of the mitochondrial electron transfer system (ETS) can provide comprehensive information on metabolite uptake, enzyme activities, and coupling of electron transfer and phosphorylation of ADP to ATP. We provide comprehensive mitochondrial oxidative phosphorylation analysis services.
Mitochondrial Membrane Potential Analysis
Monitoring mitochondrial membrane potential provides a sensitive indicator for early detection of mitochondrial integrity. We offer reliable and effective assays for measuring mitochondrial membrane potential using fluorescent detection methods on various testing platforms such as microplate readers, fluorescence microscopy, or flow cytometry.
Mitochondrial Calcium Ion Detection
Excessive accumulation of calcium ions within the mitochondria can lead to mitochondrial dysfunction and oxidative stress. Therefore, precise monitoring of mitochondrial calcium is crucial. We offer tailored and comprehensive services for detecting mitochondrial calcium ions, designed to expedite the success of our client's projects.
Mitochondrial ROS Analysis
Studies have shown that more than 95% of the body's reactive oxygen species (ROS) originate from the mitochondria, and oxidative stress resulting from their imbalance is associated with cellular growth and proliferation, developmental differentiation, aging, apoptosis, as well as various physiological and pathological processes. We are dedicated to providing customized one-stop services for detecting mitochondrial ROS.
Mitochondrial Permeability Transition Pore Analysis
The mPTP (mitochondrial permeability transition pore) is a non-specific channel that plays a significant role in cell survival and apoptosis in diverse mitochondrial diseases. Leveraging experienced experts and advanced platforms, including flow cytometry, fluorescence microscopy, and laser confocal microscopy, we deliver assay services for evaluating mitochondrial permeability transition pores.
Our Advantages
Protheragen is based on a highly stable, reproducible, and highly sensitive separation, characterization, and quantitative analysis system to provide you with a reliable, fast, and cost-effective one-stop mitochondrial function analysis service. We appreciate your trust in our expertise. Should you have any inquiries or concerns, please do not hesitate to contact us.