Peptide Antibody Conjugation Service
Along with the benefits provided by modern technology, peptide antibody conjugation (PAC) enables focused drug distribution, targeting enhancement of therapeutics, and even diagnosis complementation for obscure diseases in Biomedical research. Our company offers PAC services with therapeutical advancements that apply to rare disease peptides, and thus they could play a key role in development of those therapies.
Introduction to Peptide Antibody Conjugation
The pinnacle in advanced scientific treatment for less common diseases is PAC, through which a new realm of research is made possible. By combining the exquisite targeting peptides are recognized for and the aggressive nature ascribed to antibodies, unprecedented opportunities have been unlocked for targeted therapies in various disease – conditions, mainly cancer.
PAC stands for peptide antibody conjugation, which, along with other forms of modern technology, is a must to be included in any biomedical research multidisciplinary field. It offers a range of benefits all in targeted diagnostics and therapeutics, and even to the extent of accurate global positioning system for the medicine – precise medicine, as what is supposed to be the goal with rare diseases.
Fig.1 The peptide conjugation to the antibody via amine coupling (Kiyoshi, Masato, et al. 2023)
PAC has emerged as indispensable tools in the field of biomedical research, offering multifaceted advantages such as targeted drug delivery, augmented therapeutic effectiveness, and enhanced diagnostic capabilities. The convergence of antibodies and peptides within PAC has revolutionized the landscape of rare diseases, propelling the field toward personalized and more efficacious therapeutics strategies.
Our Services
Our range of services for peptide antibody conjugation encompasses quality, stability, and efficacy of these conjugates. We have a group of scientists and advanced state-of-the-art facilities to provide analytical techniques and assays to evaluate PAC properties and performance.
Peptide Design and Synthesis (Optional)
Through careful analysis of target antigens, we can engineer peptide sequences that possess optimal binding affinity and specificity.
Optional Gene Therapies
The success of PAC hinges upon the appropriate selection of antibodies with high binding affinity towards the target antigen. Our company offers a vast array of monoclonal and polyclonal antibodies for different applications.
Peptide Antibody Conjugation
We can provide cutting-edge conjugation methodologies, such as site-specific conjugation, to ensure a stable and homogeneous PAC product and preserve the native activity of the antibody and peptide.
Characterization of PAC
Comprehensive biochemical characterization includes:
- Conjugation efficiency
- Drug-to-antibody ratio (DAR)
- Stability
- The binding affinity of the PAC towards the target antigen
Our PAC offering is designed to help biological professionals optimize your research efforts and facilitate drug development programs for orphan diseases as clearly and promptly as possible. If you are interested in our services, please feel free to contact us for more details and quotation information of related services.
Reference
- Kiyoshi, Masato, et al. "Specific peptide conjugation to a therapeutic antibody leads to enhanced therapeutic potency and thermal stability by reduced Fc dynamics." Scientific Reports 13.1 (2023): 16561.
All of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.