Protheragen is a service provider specializing in providing comprehensive one-stop solutions for preclinical drug discovery & development targeting rare diseases. We offer a full range of services, including biomarker discovery, customized assay design, in vitro and in vivo model development, pharmacokinetic analysis, and safety evaluation. With a global focus, we aim to support pharmaceutical companies and researchers in accelerating the development of innovative therapeutics for rare diseases. Our expertise, combined with client-centric approach, ensures the delivery of high-quality results tailored to meet the unique needs of each project.
Rare diseases are those conditions that affect a population proportionate to 0.65-1 per cent, according to the World Health Organization (WHO). Although rare diseases are not common, more than 7,000 identified types of rare disease exist in the world and 300 million patients have them. They typically emerge as inherited, multifactorial, fatal, degenerative, autoimmune, systemic, chronic, life-threatening or fatal disease patterns.
Due to the complexity and diversity of rare diseases, diagnosis and treatment are more challenging, but the study of these diseases is important for the advancement of science.
Diagnosis of rare diseases is a complex and multi-step process that often requires a combination of technologies and approaches to achieve an accurate diagnosis. Below are some key steps and strategies for developing diagnostic reagents for rare diseases.
Artificial Intelligence Analysis
Indication: The analysis provided by our company is for research only and cannot be used to diagnose patients.
Rare Disease Target Identification
Rare Disease Therapeutics Development
By employing advanced bioinformatics analysis, our company can uncover valuable insights into the genetic basis of diseases, facilitating the development of targeted therapies and personalized treatment plans. Meanwhile, our company specializes in biomarker discovery and validation, utilizing advanced techniques such as genomics, proteomics, and metabolomics.
Diagnostic Development
Our company stands at the forefront of the burgeoning field of rare disease therapeutics technology. We have carefully established a sound and mature therapy development process system, from target discovery to preclinical research, designed to meet your specific needs.
Therapeutic Development
Drug repurposing, a practice also referred to as drug repositioning or drug reprofiling, entails repurposing existing compounds for novel therapeutic applications in different diseases. We excel in screening and evaluating these compounds, identifying their potential for new therapeutic purposes, particularly in the realm of rare diseases.
Drug Repurposing
Rare disease models encompass experimental systems designed to emulate the pathophysiology and clinical manifestations of rare diseases within a controlled laboratory environment. Our expertise spans the generation, validation, and characterization of rare disease models, including the development of genetically engineered models, transplant models, humanized models, and other models.
Disease Model Development
Drawing upon our extensive expertise in rare disease therapy research, and bolstered by a legacy of excellence, innovation, and unwavering customer support, our company offers comprehensive drug safety evaluation services to both established biopharmaceutical companies and emerging scientific research institutions, including general toxicology, genetic toxicology, developmental and reproductive toxicity.
Drug Safety Evaluation
Pharmacokinetics (PK) encompasses the study of drug absorption, distribution, metabolism, and excretion, collectively referred to as "ADME." We offer a comprehensive range of pharmacokinetic services, spanning from early drug discovery to preclinical research, with a singular focus on expediting your research endeavors in the realm of rare disease treatment.
Pharmacokinetics
As a premier provider in rare disease research, we are dedicated to meeting all your research needs. We offer top-quality reagents, comprehensive one-stop services, and complete solutions to support your groundbreaking discoveries.
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