Peptide Synthesis Service
Peptides have emerged as potent catalysts for advancing the diagnosis and therapeutics of rare diseases due to their distinct biological activities. Our company specializes in delivering high-quality peptide synthesis services and possesses a range of peptide synthesis platforms that can aid in your research endeavors aimed at developing peptide therapies for rare diseases.
Introduction to Peptide Synthesis
Peptide synthesis is the process of linking amino acids in the order of C-terminus (carboxylic end) to N-terminus (amino end). Since the successful development of the solid-phase peptide synthesis method by Merrifield in 1963, peptide synthesis has been continuously improved and refined and has become a common technique in the development of rare disease drugs. It serves as the foundation for the development of rare disease polypeptide therapy.
Fig.1 Methods for generating libraries of genetically encoded cyclic peptides in drug discovery (Sohrabi, Catrin, et al. 2020)
Synthetic polypeptides have shown promise in rare disease therapy. They can be used as probes for diagnosis and imaging, coupled with nanomaterials for targeted therapy, or developed as peptide vaccines to activate the immune system for prevention. Synthetic peptides have demonstrated good stability and can target specific molecules or signaling pathways in tumor cells.
Our Services
By leveraging our advanced synthetic strategies, high-throughput screening, and structural studies, our company provides comprehensive peptide synthesis services, ensuring that your peptide synthesis needs are met with various quality and purity requirements.
- Custom Peptide Synthesis
Our services encompass regular peptide synthesis and fast peptide synthesis options, which you can choose according to your experimental needs and budget.
| Contents | Regular Peptide Synthesis | Fast Peptide Synthesis |
|---|---|---|
| Cycle | 2-3weeks | 1-2weeks |
| Sequence Length | Up to 200 AA | Up to 25 AA |
| Purity | Crude to >98% | Crude to >98% |
| Quantity | mg to kg | 1-100 mg |
- Peptide Library
Our high-throughput parallel peptide synthesis platform has facilitated a range of cost-effective peptide libraries and an array of services to meet your research needs in structural biology, drug discovery, and vaccine development.
| Contents | Crude Peptide Library | Purified Peptide Library | Crude Micro-scale Peptide Library | Purified Micro-scale Peptide Library |
|---|---|---|---|---|
| Cycle | 2-3weeks | 3-4weeks | 3-4weeks | 3-4weeks |
| Sequence length | 5-25 AA | 5-25 AA | 5-20 AA | 5-20 AA |
| Purity | Crude | >70% to >98% | Crude | >70% |
| Quantity | 1-20 mg | 1-9 mg | 0.2-0.5 mg | 0.2-0.5 mg |
| Deliverable format | Lyophilized peptides in 96-well plates or individual vials | Lyophilized or liquid (suspended in 50% (v/v) acetonitrile/water containing 0.05% TFA) in 96-tube plates | ||
| Quality documents | COA, HPLC, and MS | |||
Project Workflow
By choosing our company for peptide synthesis service, researchers can benefit from our cutting-edge technologies and customized solutions. If you are interested in our services, please feel free to contact us for more details and quotation information of related services.
Reference
- Sohrabi, Catrin, et al. "Methods for generating and screening libraries of genetically encoded cyclic peptides in drug discovery." Nature Reviews Chemistry 4.2 (2020): 90-101.
All of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.