Reconstructed Skin Development Service

Protheragen is engaged in the development of high-quality reconstructed skin models which can aid rare skin disease research, improve drug testing, and optimize therapeutic development efforts. Reconstructed skin models provide an accurate, futuristic solution to typical in vivo systems. They provide a dynamically composite portrayal of human skin and serve as an alternative for outdated animal models.

Introduction to Reconstructed Skin Model

Reconstructed skin models are ethical alternatives to traditional animal models as they aid in advanced research with ease. The models include both the dermal and epidermal layers which allows for better simulations of human skin making them optimitive for use.

Fig.1 Histological Comparison of Native Skin and Reconstructed Skin Models. (Rodrigues Neves and Gibbs, 2021)

Developments in the field have shown for better simulation of disease progression and improve the testing of therapeutic measures, components of dynamic perfusion and immune systems are utilized which helps in complexity. Reconstructed skin models are increasingly useful for the controlled study of rare skin diseases, drug evaluation, and the testing of new treatments in an environment that is relevant to humans.

Applications of Reconstructed Skin Models

Fundamental Research

In the efforts of more progressive skin disease research, these models are fast becoming essential tools. Reconstructed skin models pose endless opportunities for investigation at the cellular, tissue, and organ level and as a result, replicate the structure and function of human skin.

Diseases Modeling

Reconstructed skin models are progressively being adopted as replacements for animal models to study different skin diseases since they are more precise, reproducible, and economical. Such models are very useful in studying psoriasis, atopic dermatitis, and other genetically-induced skin diseases.

Drug Efficacy and Toxicity Testing

Reconstructed skin models are progressively being adopted as replacements for animal models to study different skin diseases since they are more precise, reproducable, and economical. Such models are very useful in studying psoriasis, atopic dermatitis, and other genetically induced skin diseases.

Our Services

Protheragen is focused on providing an all-inclusive service range with respect to the development of the reconstructed skin models for the research of exotic skin conditions. Expert scientists and researchers on our team leverage elaborate tissue engineering methods along with their unparalleled experience to develop innovative and accurate reconstructed skin models that guarantee precision and reliability during all phases of the development process.

Reconstructed Skin Development Service

Protheragen has customized services for the development of reconstructed skins that serve different skin research purposes. Using advanced tissue engineering methods, televisions and reconstructive models of the skin with specific modifications are created. These models are reliable for investigating exotic diseases of the skin, as they recreate the architecture and physiology of the human skin.

Types of Reconstructed Skin Models

Why Choose Us?

Protheragen Protheragen offers an all-in-one complete set of services for preclinical development, including the development of reconstructive models of skin for skin disease research. From diseases model development to drug safety evaluation, our services support every stage of your research process. If you are interested in our services, please don't hesitate to contact us.

References

• Hofmann, E., et al. "Modelling the Complexity of Human Skin in Vitro." Biomedicines 11.3 (2023).
• Rodrigues Neves, C., and S. Gibbs. "Progress on Reconstructed Human Skin Models for Allergy Research and Identifying Contact Sensitizers." Curr Top Microbiol Immunol 430 (2021): 103-29.

All of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.