A subtype of mitochondrial disorders, eye-specific mitochondrial diseases, is characterized by ocular structure and dysfunctions. These diseases stem from mutations in the mitochondrial DNA and are considered rare. These disorders may cause deterioration of vision, ophthalmoplegia, and other eye-related symptoms. Protheragen has established itself as one of the leaders in researching mitochondrial diseases. We have tremendous experience and an advanced platform, which will allow us to offer the highest quality service in research for eye-specific mitochondrial diseases.
Autosomal Dominant Optic Atrophy
Progressive loss of vision, which is the hallmark of autosomal dominant optic atrophy (ADOA), places it in the category of uncommon mitochondrial genetic disorders. Most individuals report experiencing some form of visual impairment in their youth, which slowly worsens over time, culminating in optic nerve degeneration and blindness.
Chronic Progressive External Ophthalmoplegia
Chronic progressive external ophthalmoplegia (CPEO) is a rare condition that falls under the class of mitochondrial disorders associated with the restriction of eye movement coupled with progressive drooping of the eyelids. Some individuals report limited eye movement, eye tremors, and slow paralysis of ocular motion.
Leber Hereditary Optic Neuropathy
Leber hereditary optic neuropathy (LHON) is a genetic phenomenon that is relatively uncommon, affecting a person’s eyesight through the optic nerve and resulting in progressive bilateral blindness. This condition usually presents itself in early adulthood and occurs more frequently in males than in females.
Neuropathy Ataxia Retinitis Pigmentosa Syndrome
NARP syndrome, also referred to as neuropathy, ataxia, and retinitis pigmentosa syndrome, is an unusual disorder that stems from mitochondrial genetics and is identified by the presence of neuropathy, ataxia, and retinitis pigmentosa.
Our Services
Protheragen's expert team is focused on fundamental mechanistic studies as well as advanced therapeutic development, thus offering a comprehensive range of research services. You may be studying eye-specific mitochondrial diseases along with novel therapeutic options, and we readily have the skillset, resources, and teamwork to help elevate your research.
Therapeutics Development Services for Mitochondrial Diseases
The focus of our research lies in the development of pharmaceuticals targeting eye-specific mitochondrial diseases, encompassing drug screening and the advancement of drug delivery systems.
We provide an extensive array of services tailored to the development of molecular drugs.
Our Advantages
Protheragen provides ample services and support towards the research and therapeutics development of eye-specific mitochondrial diseases. For more detailed information about these diseases and the services we offer, please feel free to contact us.
