Geotrichum candidum and Geotrichum species cause the rare fungal infection known as geotrichosis, and both its diagnosis and therapeutic are difficult in their own right. Our company's chief focus on geotrichosis, and other such rare fungal diseases, is unmatched globally in being able to provide holistic services to researchers and scientists alike.
Overview of Geotrichosis
Geotrichosis is a rare opportunistic infection caused by fungi, and it primarily affects immunocompromised individuals, such as those infected with HIV/AIDS, cancer individuals, and individuals who have undergone organ transplants. This same fungus which disease manifestations as other common pathogens like Candida species, has a wide range of appearances like pulmonary, cutaneous, gastrointestinal, disseminated, etc. forms of infections.
Fig.1 Microscopic observation of Geotrichum. (Álvarez-Rodríguez, J. C., et al., 2023)
Pathogenesis of Geotrichosis
Geotrichum is a yeast-like fungus that can be found in a variety of locations such as soil, water, and dairy products. Organisms can be contracted through inhalation or ingestion of spores and as a result can form multi-faceted infections such as pulmonary, cutaneous, and gastrointestinal systems spread throughout the body. Fungus infections pose a much higher risk to immunocompromised individuals because the spore can transit from the primary infection site to other organs, further complicating the infection.
Vaccine and Therapeutic Development for Geotrichosis
Vaccine of Geotrichosis
The invention of the geotrichosis vaccine remains in early stages because the complexity of the fungal pathogens, and the immune responses fungal pathogens create is always inconsistent.
Therapeutic of Geotrichosis
In geotrichosis therapy, amphotericin B, voriconazole, posaconazole, and micafungin are the standard antifungal agents used. Sometimes combination therapy is required especially in the severe forms of the disease.
Our Services
Our comprehensive service includes modern lab equipment, professional consultations, a variety of research tools, as well as any guidance needed. We are capable of meeting the specific needs of researchers through our model of infectious disease, vaccine development, and therapeutic development platforms.
Vaccine Development Platforms
Therapeutic Development Platforms
Infectious Disease Models
Animal models are vital tools in the study of the etiology, therapeutic, and prevention of infectious diseases. We provide a range of animal models of geotrichosis which help in understanding the geotrichosis pathogenesis, testing new therapeutical approaches as well as formulating effective measures.
Animal models can be tailored to mimic different aspects of geotrichosis, including pulmonary, cutaneous, gastrointestinal, and disseminated infections, allowing researchers to study various disease manifestations.
Optional Models: Mouse model inoculated with Geotrichum candidum, etc.
Why Choose Us
We are of assistance to all the scientists in a phenomenal way in speeding up the entire research from the very start of an investigation to more sophisticated research processes. Our company is a partner of scientists who wish to make a notable impact in the field of infectious disease therapy.
If you would like to know more about the services we offer, please do not hesitate to reach out to us
Reference
- Álvarez-Rodríguez, José Camilo et al. "Geotrichosis: fungemia in a patient with acute lymphoblastic leukemia." Biomedica: revista del Instituto Nacional de Salud 43 (2023): 32-40.
All of our services and products are intended for preclinical research use
only and cannot be used to diagnose, treat or manage patients.
