Infectious Diseases
Effective diagnostic tools, drugs, and therapies are critical to combating infectious diseases. Our company is at the forefront of infectious disease drug and therapeutic development services, providing comprehensive solutions to accelerate research into rare infectious diseases relevant to the pharmaceutical industry.
Overview of Infectious Diseases
Infectious diseases encompass a spectrum of illnesses triggered by pathogenic microorganisms, such as viruses, bacteria, fungi, and parasites. These microorganisms infiltrate the host's body, proliferate, and disrupt normal bodily functions, giving rise to an array of symptoms and potential complications. Transmission of infectious diseases can occur through person-to-person contact, ingestion of contaminated food or water, or via vectors like mosquitoes or ticks.
Pathogenesis of Infectious Diseases
Various factors contribute to the development and spread of infectious diseases. Pathogens are the primary causative agents, but other factors play a role in their transmission and severity. Some key causes include:
- Host Factors: Individual factors, including age, immune status, underlying health conditions, and genetic predisposition, can influence the susceptibility to and severity of infectious diseases.
- Environmental Factors: Environmental conditions, such as poor sanitation, overcrowding, and inadequate access to clean water, can contribute to the spread and persistence of infectious diseases.
- Pathogens: Bacteria, fungi, parasites, and viruses serve as the key microorganisms accountable for instigating infectious diseases. Each pathogen has its unique mechanisms of infection.
Fig.1 Examples of epidemic periods associated with different eras of human transportation. (Baker, Rachel E., et al., 2022)Therapy Development for Infectious Diseases
Antimicrobial Therapy
This form of therapy involves the use of drugs, such as antivirals, antibiotics, antifungals, or antiparasitic agents, to directly target and eliminate the infectious agent. The selection of antimicrobial therapy relies on the identification of the pathogen and its susceptibility to particular drugs.
Immunotherapy
Immunotherapeutic approaches harness the body's immune system to fight against infectious diseases. This can involve the administration of immune-boosting agents, such as cytokines or monoclonal antibodies, to enhance the immune response and aid in pathogen clearance.
Vaccine Therapy
Vaccines are a crucial preventive measure against infectious diseases. They stimulate the immune system to recognize and remember specific pathogens, enabling a rapid and effective immune response upon subsequent exposure. Vaccines can prevent viral, bacterial, and some parasitic infections.
Our Services
The development of diagnostics and therapeutics for infectious diseases can take various forms, depending on the specific pathogen, severity of the infection, and other factors. At our company, we are dedicated to advancing the development of innovative therapies for infectious diseases.
Rare Types of Infectious Diseases
- American Trypanosomiasis
- Candidiasis
- Clostridium difficile infections
- Coccidioidomycosis
- Cryptococcosis
- Malaria
- Melioidosis
- Proteus Syndrome (PS)
- Schistosomiasis
- Toxoplasmosis
- Tuberculosis (TB)
Therapy Development Platforms
We offer a wide range of infectious diseases animal models, including in vivo models for bacterial, viral, fungal, and parasitic infections. These models allow for the evaluation of therapeutic efficacy and safety, aiding in the development of effective therapies.
If you are interested in our services, please feel free to contact us for more details and quotation information of related services.References
- Baker, Rachel E., et al. "Infectious disease in an era of global change." Nature Reviews Microbiology 20.4 (2022): 193-205.
- Van Seventer, Jean Maguire, and Natasha S. Hochberg. "Principles of infectious diseases: transmission, diagnosis, prevention, and control." International encyclopedia of public health (2017): 22.
All of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.