Black piedra is a form of fungal infection that is rare and is also called trichomycosis nodosa black. Our company constituted by specialists from different disciplines, remains actively engaged in research and innovation on how to deal with black piedra, we are able to service and assist researchers throughout all the stages of their scientific research.
Overview of Black Piedra
Black piedra is caused by a fungus called Piedraia hortae which manifests in the form of small black nodules that can be found on the shaft of hair. Black piedra is believed to occur mostly in places with humid and subtropical temperatures including regions in South America, Central America, and parts of Asia. As for the hair follicles themselves, black piedra is known to cause nodule development which makes the hair strands more prone to breakage.
Symptoms of black piedra may include:
- Small, hard nodules on hair strands
- Dark brown or black color of the nodules
- Itching or irritation in the affected area
- Hair breakage or loss
Fig.1 Blackish appearance and microscopic examination of Piedraia hortae colonies. (Junior, H. L. A., et al., 2024)
Pathogenesis of Black Piedra
The hair cuticle and the hair shaft cortex should be integrated on the black piedra noduli which results from the fungus Piedraia hortae. Discussions on the primary mechanisms of causation as being proficient of hair shaft being attached and perhaps penetration more salient in pondering. Black piedra also has geography, hygiene, and climate as determining factors.
Therapeutics Development for Black Piedra
Topical antifungal agents
Topical antifungal agents ketoconazole and miconazole have almost always proven to be beneficial therapeutic agents for black piedra.
Oral antifungal drugs
Oral antifungals iatraconazole, and terbinafine are considered systemic therapy useful for people with extensive or recurrent infections.
Our Services
Our firm provides comprehensive support to researchers and scientists who are struggling with black piedra and other similar infections. From drug discovery to disease modeling, and developing diagnostics and therapeutics, we assist in the commercialization of scientific innovations.
Featured Services of Black Piedra
Infectious Disease Models
- Rat model of Piedraia hortae infection
- Mouse model of Piedraia hortae infection
- Guinea pig model of Piedraia hortae infection
- Rabbit model of Piedraia hortae infection
- Others
Why Choose Us
To enable the research of diseases such as black piedra in more efficient manners, we provide the necessary resources equipment spaces, and materials. The focus is to encourage therapy research and innovation for some of the most problematic diseases for the researcher by providing access to high-quality services and platforms.
If you are interested in our service, we invite you to reach out to us for more information.
References
- Piquero-Casals, Jaime et al. "Black Piedra in an Amerindian Girl with Oculocutaneous Albinism Type 2." Dermatology practical & conceptual 13.3 (2023): e2023165.
- Junior, Hiram Larangeira de Almeida et al. "Piedraia hortae: biofilm formation and its importance in the pathogenesis of Piedra nigra (black piedra)." Anais brasileiros de dermatologia S0365-0596 (2024): 00141-7.
All of our services and products are intended for preclinical research use
only and cannot be used to diagnose, treat or manage patients.