Rare Allergic Diseases
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Please note that we are not a pharmacy or clinic, so we are unable to see patients and do not offer diagnostic and treatment services for individuals.

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Rare Allergic Diseases Drug Safety Evaluation Services

Drug safety evaluation involves analyzing therapeutic drug safety by conducting laboratory tests and animal in vitro studies. Protheragen utilizes its extensive experience in rare disease therapy research to offer full drug safety evaluation solutions to both established and emerging biopharmaceutical firms and research institutions. Our services guarantee quality assurance while promoting innovation and delivering strong customer support.

Overview of Drug Safety Evaluation for Rare Allergic Diseases

The ongoing advancement of new pharmaceutical drugs and formulas has resulted in multiple safety challenges. Drug safety evaluation aims to establish safe dosage levels and administration schedules that will minimize adverse event risks. New drugs must undergo this evaluation to progress to final trials and receive approval. Traditional methods for drug safety evaluation fail to satisfy modern requirements which pushes research to create quicker and more accurate safety assessment technologies.

Our Services

As a comprehensive research service provider, Protheragrn is equipped with the capabilities and resources to deliver expert drug safety evaluation services, ensuring we can swiftly adapt to the evolving needs of your rare allergic disease research projects.

General Toxicology Evaluation

  • Dose Range Finding Studies
  • Single-dose Toxicity Evaluation
  • Repeated-dose Toxicity Evaluation

Genetic Toxicology Evaluation

  • Chromosomal Aberration Assay
  • Microwell Micronucleus Assay
  • Bacterial Mutation Assay

Developmental and Reproductive Toxicity Evaluation

  • Fertility and Early Embryo Development Toxicity
  • Embryo-fetal Development Toxicity
  • Perinatal Toxicity

Immunogenicity and Immunotoxicity Evaluation

  • T-cell Dependent Antibody Response (TDAR)
  • Tissue Cross Reactivity (TCR)
  • White Blood Cell Differential Count

Local Toxicity Evaluation

  • Hemolysis Evaluation
  • Allergy Evaluation
  • Irritation Evaluation

Phototoxicity Evaluation

  • Photoallergy Studies in Guinea Pigs
  • Photodynamic Drugs Evaluation
  • 3D Epidermal Cell Systems Evaluation

Tissue Cross-Reactivity Evaluation

  • Automated IHC Processing
  • Monoclonal Safety Evaluation
  • Slide Evaluation and Interpretation

Safety Pharmacology Evaluation

  • Central Nervous System Evaluation
  • Cardiovascular System Evaluation
  • Respiratory System Evaluation
  • hERG Tests

Toxicokinetics Evaluation

  • TK/TOX Analysis
  • Metabolite Analysis
  • Immunogenicity Analysis
  • Microsampling for TK Profiling

Applications of Drug Safety Evaluation

Toxic dose identification.

Toxic Dose Identification

Determine the toxic dose following a single administration and assess the dose range that may cause toxicity with repeated administrations, providing a foundation for further toxicity research.

Safe dosage range determination.

Safe Dosage Range Determination

Identify the dose range where the drug is effective without inducing toxic side effects, whether given once or multiple times, offering essential information for drug safety and side effect monitoring.

Toxic target organs identification.

Toxic Target Organs Identification

Discover the specific organs or tissues affected by the drug's toxic effects in animals, providing a basis for monitoring adverse effects and guiding structural modifications of new drugs.

Toxicity reversibility assessment.

Toxicity Reversibility Assessment

Evaluate whether the drug's toxic effects on the body are reversible, along with the required recovery extent and duration, to inform ongoing research on new drug development.

Our Advantages

Time-saving services with high efficiency

Professional and experienced scientists

Complete project designing and reporting

Numerous service cases and customer praise

With a research team rich in expertise in drug safety evaluation, Protheragen offers professional communication and problem-solving assistance to ensure we can promptly adapt to the changing needs of your rare allergic disease therapy research projects. If you are interested in our services, please feel free to contact us for more information.

All of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.

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